Chromosomes contain both the raw code for life and the instructions for its use. We are interested in discovering the rules that govern chromosome structure and function at the molecular level. Our efforts are focused on how nucleosomes and chromosome-segregation machines are organized in situ. We test both old and new hypotheses of chromosome-related activities by perturbing cells and then observing their structural changes by electron cryotomography. Revolutionary technologies will help us learn about chromosome transactions in situ with unprecedented detail.


April 2022 - Welcome to Saayli.

April 2022 - Farewell to Jia Hui, Salihah, and Qingpin.

April 2022 - Olivia's Meiotic Triple Helix (MTH) paper is published!