Welcome

We've moved! Our lab is now at the University of Virginia, based in the Department of Molecular Physiology and Biological Physics and the Center for Membrane and Cell Physiology. Please contact us if you're interested in joining.

Chromosomes contain both the raw code for life and the instructions for its use. We are interested in discovering the rules that govern chromosome structure and function at the molecular level. Our efforts are focused on how nucleosomes and chromosome-segregation machines are organized in situ. We test both old and new hypotheses of chromosome-related activities by perturbing cells and then observing their structural changes by electron cryotomography. Revolutionary technologies will help us learn about chromosome transactions in situ with unprecedented detail.

News

Feb 2025 - Our G0/G1 fission yeast nucleus study is now online at JCS! Congrats to Zhi Yang and Shujun!

Jan 2025 - Welcome to Christine!

Jan 2025 - We've moved to our new home at MPBP in UVA!