† equal contributions; * corresponding authors
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Ng, C., Deng, L., Chen, C., Lim, H.H., Shi, J., Surana, U., and Gan, L. (2018), A multi-scale model of the yeast chromosome-segregation system.
(bioRχiv preprint)  Raw data: EMPIAR-10159    Exemplar tomograms: EMD-6912, EMD-6914

Cai, S., Chen, C., Tan, Z.Y., Huang, Y., Shi, J., and Gan, L. (2018), Cryo-ET reveals the macromolecular reorganization of S. pombe mitotic chromosomes in vivo. PNAS in press
PDF file  (bioRχiv preprint)  Raw data: EMPIAR-10125    Exemplar tomogram: EMD-6846

Cai, S.Böck, D.Pilhofer, M.*, and Gan, L.* (2018), The in situ structures of mono-, di-, and trinucleosomes in human heterochromatinMol Biol Cell 29: 2450-2457
PDF file  (bioRχiv preprint)  Raw data: EMPIAR-10179   Exemplar tomograms/averages: EMD-6948, EMD-6949, EMD-6950

Cai, S., Song, Y., Chen, C., Shi, J., and Gan, L. (2018), Natural chromatin is heterogeneous and self associates in vitro. Mol Biol Cell 29: 1652-1663
PDF file  (bioRχiv preprint)  Raw data: EMPIAR-10098   Exemplar tomograms: EMD-6737 

Chen, C., Lim, H.H., Shi, J., Tamura, S., Maeshima, K., Surana, U., and Gan, L. (2016), Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo. Mol Biol Cell 27: 3357-3368
PDF file  (
bioRχiv preprint)  Raw data: EMPIAR-10062   Exemplar tomogram: EMD-8157

Gan, L., Ladinsky, M.S. and Jensen, G.J. (2013), Chromatin in a marine picoeukaryote is a disordered assemblage of nucleosomes. Chromosoma 122: 377-386
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Priori to 2011
Gan, L., Ladinsky, M.S. and Jensen, G.J. (2011), Organization of the smallest eukaryotic spindle. Current Biology 21: 1578-1583

Gan, L., Chen, S. and Jensen, G.J. (2008), Molecular organization of Gram-negative peptidoglycan. PNAS 105 (48): 18953-18957

Henderson, G.P., Gan, L., and Jensen, G.J. (2007), 3-D ultrastructure of O. tauri: electron cryotomography of an entire eukaryotic cell. PLoS One 2(8): e749

Fu, C.Y., Wang, K., Gan, L., Lanman, J., Khayat, R., Young, M.J., Jensen, G.J., Doerschuk, P.C., Johnson, J.E. (2010), In vivo assembly of an archaeal virus studied with whole-cell electron cryotomography. Structure 18: 1579-1586

Chen, S., McDowall, A., Dobro, M.J., Briegel, A., Ladinsky, M., Shi, J., Tocheva, E., Beeby, M., Pilhofer, M., Ding, H. J., Li, Z., Gan, L., Morris D.M., and Jensen, G.J. (2010), Electron Cryotomography of Bacterial Cells. JoVE 39: e1943

Gertsman, I., Gan, L., Guttman, M., Lee, K., Speir, J.A., Duda, R.L., Hendrix, R.W., Komives, E.A., Johnson, J.E. (2009), An unexpected twist in viral capsid maturation. Nature 458: 646-650

Lee, K.K., Gan, L., Tsuruta, H., Conway, J.F., Hendrix, R.W., Steven, A.C., Duda, R.L., Johnson, J.E. (2008), Virus capsid expansion driven by the capture of mobile surface loops. Structure 16: 1491-1502

Gan, L. and Johnson, J.E. (2008), An optimal exposure strategy for cryoprotected virus crystals with lattice constants greater than 1000Å. J. Synchrotron Rad. 15: 223-226

Szymczyna, B.R., Gan, L., Johnson, J.E., Williamson, J.R. (2007), Solution NMR studies of the maturation intermediates of a 13MDa viral capsid. JACS 129: 7867-7876

Iancu, C.V., Tivol, W.F., Schooler, J.B., Dias, D.P., Henderson, G.P., Murphy, G.E., Wright, E.R., Li, Z., Yu, Z.H., Briegel, A., Gan, L., He, Y.N., Jensen G.J. (2006), Electron cryotomography sample preparation using the Vitrobot. Nature Protocols 1: 2813-2819

Gan, L., Speir, J.A., Conway, J.F., Lander, G., Cheng, N., Firek, B.A., Duda, R.L., Hendrix, R.W., Liljas, L., Johnson, J.E. (2006), Capsid conformational sampling in HK97 maturation visualized by X-ray crystallography and Cryo-EM. Structure 14: 1655-1656 (Cover)

Wikoff, W.R., Conway, J.F., Tang, J., Lee, K.K., Gan, L., Cheng, N., Duda, R.L., Hendrix, R.W., Steven, A.C., and Johnson, J.E. (2006), Time-resolved molecular dynamics of Bacteriophage HK97 capsid maturation interpreted by electron cryo-microscopy and X-ray crystallography. J. Struct. Biology 153: 300-306 (Cover)

Lee, K.K., Gan, L., Tsuruta, H., Hendrix, R.W., Duda, R.L., Johnson, J.E. (2004), Evidence that a local refolding event triggers maturation of HK97 bacteriophage capsid. J. Mol. Biol. 340: 419-433

Gan, L., Conway, J.F., Firek, B.A., Cheng, N., Hendrix, R.W., Steven, A.C., Johnson, J.E., Duda, R.L. (2004), Control of crosslinking by quaternary structure changes during bacteriophage HK97 maturation. Molecular Cell 14: 559-569

Tomassini, J.E., Boots, E., Gan, L., Graham, P., Munshi, V., Wolanski, B., Fay, J.F., Getty, K., LaFemina, R. (2003), An in vitro Flaviviridae replicase system capable of authentic RNA replication. Virology 313: 274-285

Martin, W.L., West, Jr. A.P., Gan, L., Bjorkman P.J. (2001), Crystal structure at 2.8Å of an FcRn/heterodimeric Fc complex: mechanism of pH dependent binding. Molecular Cell 7: 867-877

Review articles
Gan, L. and Jensen, G.J. (2012), Electron tomography of cells. Q. Rev. Biophys. 45: 27-56